Nickel(II) complexes of N–CH2CF3 cyclam derivatives as contrast agents for F magnetic resonance imaging
نویسندگان
چکیده
a Department of Inorganic Chemistry, Faculty of Science, Charles University (Univerzita Karlova), Hlavova 2030, 128 43 Prague 2, Czech Republic. Tel.: +420-22195-1261. Fax: +420-221951253. E-mail: [email protected]. b Department of Radiodiagnostic and Interventional Radiology, Magnetic Resonance Unit, Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, Prague 4, 140 21 Czech Republic. c NMR laboratory, Faculty of Science, Charles University (Univerzita Karlova), Hlavova 2030, 128 43 Prague 2, Czech Republic.
منابع مشابه
Nickel(II) complexes of N-CH2CF3 cyclam derivatives as contrast agents for (19)F magnetic resonance imaging.
Kinetically inert Ni(ii) complexes of N(1),N(8)-bis(2,2,2-trifluoroethyl)cyclams with hydrogen atoms or phosphonic acid groups in the N(4),N(11)-positions show significant (19)F NMR relaxation rate enhancement useful for 19-fluorine MRI imaging.
متن کاملA New Potential Contrast Agent for Magnetic Resonance Imaging: Iron Oxide-4A Nanocomposite
Background: Magnetic resonance imaging (MRI) contrast agents have an important role to differentiate healthy and diseased tissues. Access and design new contrast agents for the optimal use of MRI are necessary. This study aims to evaluate iron oxide–4A nanocomposite ability to act as a magnetic resonance imaging contrast agent.Materials and Methods: Iron oxide–4A nanocomposite (F4A) was syn...
متن کاملGadolinium-Diethylenetriaminepenta-Acetic acid Conjugated with Monoclonal Antibody C595 as New Magnetic Resonance Imaging Contrast Agents for Breast Cancer (MCF-7) Detection
Background: The monoclonal antibody, C595, against breast cancer cell line was conjugated with cyclic anhydride gadolinium-diethylenetriaminepenta-acetic acid (Gd-cDTPAa) to produce Gd-DTPA-C595 and used as specific breast cancer cell line (MCF-7) contrast agents in magnetic resonance imaging (MRI). Methods: After incubation of breast cancer cell line (MCF-7), with different contrast agents (G...
متن کاملBimodal magnetic resonance imaging-computed tomography nanoprobes: A Review
Bimodal imaging combines two imaging modalities in order to benefit from their advantages and compensate the limitations of each modality. This technique could accurately detect diseases for diagnostic purposes. Nanoparticles simultaneously offer diagnostic data via various imaging modalities owing to their unique properties. Moreover, bimodal nanoprobes could be incorporated into theranostic s...
متن کاملAnalytical determination of the chemical exchange saturation transfer (CEST) contrast in molecular magnetic resonance imaging
Magnetic resonance based on molecular imaging allows tracing contrast agents thereby facilitating early diagnosis of diseases in a non-invasive fashion that enhances the soft tissue with high spatial resolution. Recently, the exchange of protons between the contrast agent and water, known as the chemical exchange saturation transfer (CEST) effect, has been measured by applying a suitable pulse ...
متن کامل